Stimulation of Mouse Hair Regrowth by Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells

    July 2024 in “ Acta Histochemica ”
    Jing Wang, Qingmin Sun, Ya Shen, Qingshan Li, Yongjun Piao, Lin Gong
    TLDR Exosomes from human stem cells can help regrow hair in mice.
    The study investigates the effects of exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSC-exos) on hair regrowth in mice. The hUCMSC-exos were extracted and used to treat depilation-induced hair regrowth in C57BL/6 mice. Results showed that hUCMSC-exos significantly promoted fibroblast proliferation and accelerated hair regrowth by upregulating hair follicle stem/progenitor cells and activating the Wnt/β-catenin pathway. These findings suggest that hUCMSC-exos could be a potential therapeutic approach for treating hair loss disorders.
    Discuss this study in the Community →

    Research cited in this study

    12 / 12 results

    Related Community Posts Join

    6 / 205 results

      community My Theory Of Androgenic Alopecia

      in Research/Science  19 upvotes 4 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Musely s Exosome formulation looks interesting

      in Chat  15 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community Has anyone tried Exosomes from Musely or somewhere else?

      in Hair Systems  10 upvotes 11 months ago
      Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.

    Similar Research

    5 / 1000+ results