Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered to Overexpress Growth Factors Accelerate Outcomes in Hair Growth
January 2018
in “
The Korean Journal of Physiology and Pharmacology
”
human umbilical cord blood mesenchymal stem cells hUCB-MSCs growth factors anagen phase hair follicle neogenesis hair regrowth human dermal papilla cells hDPCs AKT/GSK3B/ß-catenin signaling pathway insulin-like growth factor binding protein-1 IGFBP-1 hair follicle cycling hair follicle morphogenesis alopecia stem cells hair growth phase hair follicle formation dermal papilla cells AKT signaling pathway insulin-like growth factor hair cycle hair follicle development hair loss
Studysummary This study found that human umbilical cord blood mesenchymal stem cells promoted hair growth by advancing anagen onset and increasing hair follicle regeneration in an in vivo model.
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