Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered to Overexpress Growth Factors Accelerate Outcomes in Hair Growth

    Dong Ho Bak, Mi Ji Choi, Soon Re Kim … Beom Joon Kim
    Studysummary This study found that human umbilical cord blood mesenchymal stem cells promoted hair growth by advancing anagen onset and increasing hair follicle regeneration in an in vivo model.
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    Research cited in this study 29

    1. Activating Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Increases Hair Inductivity FEBS Journal · 2016
    2. Assembling Composite Dermal Papilla Spheres with Adipose-Derived Stem Cells to Enhance Hair Follicle Induction Scientific Reports · 2016
    3. Human Placental Extract Exerts Hair Growth-Promoting Effects Through the GSK-3β Signaling Pathway in Human Dermal Papilla Cells International Journal of Molecular Medicine · 2015
    4. Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth Scientific Reports · 2014
    5. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    6. Therapeutic Strategy for Hair Regeneration: Hair Cycle Activation, Niche Environment Modulation, Wound-Induced Follicle Neogenesis, and Stem Cell Engineering Expert Opinion on Biological Therapy · 2013
    7. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    8. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    9. Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia British Journal of Dermatology · 2012
    10. Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay Journal of Investigative Dermatology · 2011
    11. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    12. Diagnosing and Treating Hair Loss PubMed · 2009
    13. Overexpression of mIGF-1 in Keratinocytes Improves Wound Healing and Accelerates Hair Follicle Formation and Cycling in Mice American Journal Of Pathology · 2008
    14. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    15. Hair Transplantation: Standard Guidelines of Care PubMed · 2008
    16. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007
    17. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    18. Effects of Finasteride (1 mg) on Hair Transplant Dermatologic Surgery · 2006
    19. The Hair Cycle Journal of Cell Science · 2006
    20. Effects of Finasteride (1 mg) on Hair Transplant Dermatologic Surgery · 2005
    21. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005
    22. Causes of Hair Loss and Developments in Hair Rejuvenation International Journal of Cosmetic Science · 2002
    23. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    24. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    25. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    26. Alopecia Areata: Diagnosis and Management International Journal of Dermatology · 1999
    27. Fortnightly Review: Male Pattern Androgenetic Alopecia BMJ · 1998
    28. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994
    29. The Control of Hair Growth: An Overview Journal of Investigative Dermatology · 1993