Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in Alopecia Areata

November 2023 in “ Cell Biology International ”

HU Shou-song, Jiayi Zhang, Qingqing Ji, Sai‐Sai Xie, Jingting Jiang, Haitao Ni, Xi He, Yadong Yang, Minjuan Wu

exosomes umbilical cord mesenchymal stem cells uMSCs alopecia areata hair follicular keratinocyte autoimmune attack hair follicle hair regrowth stem cells AA hair loss

TLDR Tiny particles from umbilical cord stem cells may help hair grow back in a type of hair loss.

The research article discusses the potential of exosomes derived from human umbilical cord mesenchymal stem cells (uMSCs) in promoting hair regrowth in alopecia areata (AA), a genetic disease causing hair loss due to an autoimmune attack on the hair follicle. The study highlights the therapeutic potential of uMSCs, which are easier to isolate and cultivate than MSCs from bone marrow or adipose tissue. The researchers investigated the effects of these exosomes on AA mice, suggesting that due to their easy isolation, cultivation, preparation, and storage, uMSCs and their exosomes could be used for research and clinical treatment of AA.

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