Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in Alopecia Areata

    November 2023 in “ Cell Biology International ”
    HU Shou-song, Jiayi Zhang, Qingqing Ji, Sai‐Sai Xie, Jingting Jiang, Haitao Ni, Xi He, Yadong Yang, Minjuan Wu
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    TLDR Tiny particles from umbilical cord stem cells may help hair grow back in a type of hair loss.
    The research article discusses the potential of exosomes derived from human umbilical cord mesenchymal stem cells (uMSCs) in promoting hair regrowth in alopecia areata (AA), a genetic disease causing hair loss due to an autoimmune attack on the hair follicle. The study highlights the therapeutic potential of uMSCs, which are easier to isolate and cultivate than MSCs from bone marrow or adipose tissue. The researchers investigated the effects of these exosomes on AA mice, suggesting that due to their easy isolation, cultivation, preparation, and storage, uMSCs and their exosomes could be used for research and clinical treatment of AA.
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      in Treatment  8 upvotes 1 week ago
      Exosome treatment for hair loss, derived from umbilical cord stem cells, is being considered as an option before a hair transplant. Users discuss the need for ongoing maintenance and share experiences with different exosome sources, including plant-derived options.

      community My Theory Of Androgenic Alopecia

      in Research/Science  17 upvotes 1 week ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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      in Treatments  32 upvotes 4 months ago
      The conversation discusses the effectiveness of Regenera Activia stem cells versus Cellgenic exosomes for hair loss treatment. The user has been using topical minoxidil 5% and 0.001% estradiol for a year without results.

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