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research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack

253 citations , December 2007 in “Journal of Investigative Dermatology”

This study suggests that human hair follicles may actively suppress natural killer cells, which contrasts with the observed defects in NK cell regulation in alopecia areata.

research The Pathogenesis of Primary Cicatricial Alopecias

150 citations , October 2010 in “The American Journal of Pathology”

This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.

research DERMAL-EPIDERMAL INTERACTIONS

114 citations , October 1996 in “Dermatologic clinics”

This chapter reviews laboratory models used for studying alopecia therapies but provides no new experimental findings.

research A case of patchy alopecia areata sparing lesional greying hairs

11 citations , July 2008 in “International Journal of Dermatology”

This article discusses a case of patchy alopecia areata that spares greying hairs but reports no new findings; it refers to existing literature for context.

research Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs

1 citations , March 2023 in “Clinical, Cosmetic and Investigational Dermatology”

This review discusses recent advances in understanding and treating alopecia areata, emphasizing the ongoing challenges and unmet needs in disease management; it reports no new clinical findings.

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Community Join

5 / 208 results

community Attacking DHT synergistically both locally at the scalp and systemically = Greater Success??

in Finasteride/Dutasteride 15 upvotes 1 year ago

The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Vitamin E and K deficiency (F,25)

in Research/Science 3 upvotes 4 months ago

Vitamin E and K deficiencies due to exocrine pancreatic insufficiency may affect hair growth. A scalp biopsy is recommended to check for autoimmune-related hair loss.

community An arthritis drug that can be used for Alopecia.

5 upvotes 4 years ago

An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.

community My 15+ Year Hair Loss Journey: DUPA, Recurrent Alopecia Areata, & different dosages of Min / Fin topicals - Advice needed on next steps.

4 upvotes 1 week ago

The user has been managing hair loss for over 15 years, using treatments like Minoxidil, Finasteride, and corticosteroids, while experiencing side effects and recurrent Alopecia Areata. They seek advice on progression and potential underlying conditions, questioning if their hair loss is due to an autoimmune issue beyond typical patterns.

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Learn

6 / 801 results

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

learn Stem Cell Factor

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Cetirizine

Could cetirizine help control autoimmune triggers in alopecia areata? No published trial has tested cetirizine in alopecia areata; one registered trial has not reported results. Small trials in pattern hair loss report modest benefit, so any use for alopecia areata is off-label and unproven.

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Clinics

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35
Hair Systems
AP Art Attack Hairsystem - ZweithaarspezialistDüsseldorf, Nordrhein-Westfalen · DE

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