Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/FasL-Mediated Apoptotic Signaling

    March 2014 in “ PloS one ”
    Mi Hye Kim, Sung Hoon Kim
    Studysummary In this study, Astragaloside IV was found to inhibit apoptosis-related pathways in hair follicles of mice, suggesting it may serve as an alternative therapy for hair loss.
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    Research cited in this study 6

    1. Fructus Panax Ginseng Extract Promotes Hair Regeneration in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    2. Hydroxyl Radical Mediates Cisplatin-Induced Apoptosis in Human Hair Follicle Dermal Papilla Cells and Keratinocytes Through Bcl-2-Dependent Mechanism APOPTOSIS · 2011
    3. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003
    4. Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression The FASEB Journal · 2003
    5. Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes American Journal of Physiology-cell Physiology · 2003
    6. P53 Involvement in the Control of Murine Hair Follicle Regression American Journal of Pathology · 2001

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    3. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001