Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In Vitro and Convert Hair Cycle In Vivo

    October 1998 in “ Acta dermato-venereologica
    Tomoya Takahashi, Toshikazu Kamiya, Yoshiharu Yokoo
    Studysummary This study found that proanthocyanidins from grape seeds significantly promote hair follicle cell proliferation and hair cycle transition in mice, suggesting their potential as hair growth agents. Our plain-language summary of this paper — not a Tressless recommendation.
    The 1998 study by Takahashi, Kamiya, and Yokoo found that proanthocyanidins from grape seeds significantly increased the proliferation of mouse hair follicle cells by approximately 230% compared to controls. This was part of a larger investigation into natural products for hair growth, examining around 1,000 plant extracts, and suggested that grape seed proanthocyanidins could be a promising natural agent for promoting hair growth.
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