A Molecular Wound Response Program Associated With Regeneration Initiation in Planarians

May 2012 in “ Genes & Development ”

Danielle Wenemoser, Sylvain W. Lapan, Alex W. Wilkinson, George W. Bell, Peter W. Reddien

regeneration initiation wound response immediate early genes conserved patterning factors neoblasts Runx transcription factor runt-1 serum response factor SRF sos-1 RNA interference RNAi in situ hybridizations microarray analyses

Studysummary This study identified a set of wound-induced genes in planarians that play a role in regeneration initiation, with some genes specifically activating within regenerative cells called neoblasts.

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