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GlossaryRNA interference (RNAi)

process where small RNA molecules silence specific genes

RNA interference (RNAi) is a biological process where small RNA molecules inhibit gene expression by neutralizing targeted mRNA molecules. This mechanism effectively "silences" specific genes, preventing them from producing proteins, and is used in research and medicine to study gene function and develop treatments for diseases.

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research Cashmere Growth Control in Liaoning Cashmere Goat by Ovarian Carcinoma Immunoreactive Antigen-Like Protein 2 and Decorin Genes

7 citations, March 2018 in “Asian-Australasian journal of animal sciences”

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

Pharmacological Activation of Thermo-Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

research Pharmacological Activation of Thermo-Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

12 citations, May 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

research A Molecular Wound Response Program Associated With Regeneration Initiation in Planarians

212 citations, May 2012 in “Genes & Development”

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

research Genomic Markers and Personalized Medicine in Androgenetic Alopecia: A Comprehensive Review

August 2024 in “Cosmetics”

Personalized treatments for hair loss are becoming more effective by using genetic information.

research Knockout of p16INK4a Promotes Aggregative Growth of Dermal Papilla Cells

2 citations, October 2017 in “Revista Da Associacao Medica Brasileira”

Removing p16INK4a from skin cells can lead to faster and more clumped growth, which might help with hair growth.

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community after cosmerna is out will there be another hair loss drug released in 2023?

in Treatment 10 upvotes 1 year ago

User asks if Kintor, HMI-115, or Olix will release hair loss drugs in 2023. Conversation discusses potential treatments and release dates.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 4 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Finally about to start Pyriltamide (ONLY Pyriltamide)

in Chat 63 upvotes 6 months ago

A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.