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    To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

    April 2016 in “ American Journal of Pathology ”
    Dong-Won Kim, M. Zulfiquer Hossain, Ashley Nieves … Luis A. Garza
    Studysummary The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration Cell Stem Cell · 2015
    2. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    3. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44 Journal of Investigative Dermatology · 2012
    4. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    5. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    6. Hair Follicle Regeneration Using Grafted Rodent and Human Cells Journal of Investigative Dermatology · 2007
    7. Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial-Mesenchymal Interactions ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1999