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Did you mean Keratin Gene Expression?

Glossary Keratin Gene Expression

process where cells produce keratin proteins for hair and skin

Keratin gene expression refers to the process by which cells produce keratin, a type of protein that is a key structural component of hair, skin, and nails. This involves the activation of specific genes within a cell's DNA that encode for keratin proteins, leading to their synthesis and assembly. Understanding keratin gene expression is crucial for studying hair growth, skin disorders, and conditions like alopecia.

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Research

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research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus

February 2024 in “Veterinary sciences”

This study found that canine pemphigus foliaceus skin lesions exhibit a distinct immune signature, with upregulated pro-inflammatory and Th17-related genes, showing similarities to human pemphigus. Further research using advanced sequencing is needed to better understand the disease's pathogenesis.

research Keratin 17 Impacts Global Gene Expression and Controls G2/M Cell Cycle Transition in Ionizing Radiation–Induced Skin Damage

3 citations , July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, researchers found that K17−/− mice suffered more severe hair follicle damage but showed reduced epidermal inflammation after ionizing radiation, with K17's absence leading to aberrant cell cycle progression due to altered p53 genome binding and reduced B-Myb degradation.

research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

In this study, WNT10A was identified as a key gene in the development and maturation of skin hair follicles in fetal Inner Mongolian cashmere goats.

research Differential Expression and Analysis of TBX3 Gene in Skin Tissues of Dun Mongolian Horses with and Without Bider Markings

January 2026 in “Animals”

This study researched the dun coat color in Mongolian horses, finding that variations in TBX3 expression in different skin areas are linked to Bider markings, suggesting TBX3's role in this specific pigment pattern, while further investigation is needed on its regulation.

research Gene Expression and Localization of LAMTOR3 in the Skin Cells of Liaoning Cashmere Goats

4 citations , March 2018 in “Animal biotechnology”

This study suggests that the LAMTOR3 gene may play a role in the development of hair follicles and cashmere growth in Liaoning cashmere goats by influencing the MAPK signaling pathway.

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Community Join

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community Why dont we research more on body hair

in Chat 32 upvotes 6 months ago

Body hair is more resilient than scalp hair due to different gene expressions and DHT sensitivity. Treatments like minoxidil and finasteride are used for hair loss, but they have varying effects on body and scalp hair.

community My Idea for a possible new hairloss treatment

53 upvotes 6 years ago

Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.

community Haircafe - TOPICAL minoxidil is an anti aging drug

in Minoxidil 245 upvotes 1 year ago

Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

community It’s all about the stem cells…

53 upvotes 4 years ago

Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

community Effect of Accutane(acne medication) on hair?

11 upvotes 1 week ago

Accutane can cause hair thinning in some users, with effects varying from no change to permanent hair loss. Some users reported improvements in hair and skin with treatments like Finasteride, while others experienced severe side effects, including mental health issues.

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