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To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

research To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease

23 citations, May 2016 in “American Journal of Pathology”

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

research Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development

39 citations, July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

FGF and EGF are crucial for hair follicle development and growth.

research Epithelial Expression of the Hormone Leptin by Bovine Skin

18 citations, January 2019 in “European journal of histochemistry”

Cattle skin has leptin which might control skin and hair growth.

research Epithelial-To-Mesenchymal Transition in Cutaneous Wound Healing: Where We Are and Where We Are Heading

141 citations, August 2017 in “Developmental Dynamics”

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer

45 citations, January 2020 in “International Journal of Molecular Sciences”

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

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community Why HMI115 should work if it doesn’t affect dht?

in Research/Science 16 upvotes 1 year ago

Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).

community Two Great Articles on NCBI That Summarize What We Actually Know About Finasteride Side Effects

in Finasteride 80 upvotes 5 years ago

The side effects of taking finasteride as a treatment for hair loss, with particular focus on its sexual and psychiatric side effects; research has indicated that there are high and low outliers in terms of prevalence of sexual side effects, but it is usually between 3-5%, while evidence of lasting sexual side effects comes from lower quality sources.

community Does lowering serum prolactin lower prolactin in the scalp?

in Research/Science 13 upvotes 9 months ago

The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.

community I have hairy legs and arms, and the hair grows 2+ inches long- Can I transplant it all to my head?

in Transplants 442 upvotes 3 months ago

The conversation discusses the possibility of transplanting leg and arm hair to the scalp for hair loss treatment. Minoxidil is mentioned as a potential aid for hair growth, but concerns about the effectiveness and appearance of body hair on the head are raised.

community does lowering your prolactin levels regrow hair?

in Research/Science 11 upvotes 1 year ago

The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

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