Alopecia Areata in a Patient with WNT10A Heterozygous Ectodermal Dysplasia

June 2021 in “ Dermatology Online Journal ”

Regina Liu, Amy R. Vandiver, Nicole Harter, Marcia Hogeling

alopecia areata WNT10A ectodermal dysplasia hair loss patchy hair loss genetic predisposition

TLDR A girl with a rare genetic condition affecting hair and nails also developed a common type of hair loss, suggesting a possible genetic link.

The document presents a case of a 9-year-old girl with WNT10A heterozygous ectodermal dysplasia, a rare condition affecting hair, teeth, nails, and sweat glands, who developed alopecia areata, a common form of hair loss in children. The patient had a lifelong history of poor hair and nail growth, and recently experienced patchy hair loss. This is the first reported case of alopecia areata in a patient with WNT10A heterozygous ectodermal dysplasia, suggesting the possibility of a shared genetic predisposition. The case emphasizes the importance of considering multiple pathways of hair loss in patients with underlying genetic defects.

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community Alopecia Areata Question

in Treatment 2 upvotes 3 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

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A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

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in Treatment 1 upvotes 1 year ago

A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

community Covid (likely) induced alopecia areata - now 2nd round of Covid, what can I expect?

in Treatment 1 upvotes 1 year ago

After experiencing hair loss due to alopecia areata following COVID-19 vaccination and infection, the individual saw improvement with steroid treatments and Olumiant. They paused Olumiant during a second COVID-19 infection and expressed concern about potential hair loss flare-ups.

community Onion Juice - An effective topical treatment for Alopecia Areata 🧬

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Onion juice, when applied topically, is an effective treatment for Alopecia Areata, showing significant hair regrowth in both males and females. The study suggests it could be interesting to test its effectiveness on Androgenic Alopecia.

community Nearly 40% of Adults with Alopecia Areata Taking OLUMIANT® 4-mg Saw at Least 80% Scalp Hair Coverage at 52 Weeks

in Research/Science 6 upvotes 2 years ago

Nearly 40% of adults with alopecia areata achieved at least 80% scalp hair coverage after 52 weeks of taking OLUMIANT® 4-mg. The conversation distinguishes this success from androgenetic alopecia, which is a different type of hair loss.

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