A Role of Placental Growth Factor in Hair Growth

    February 2014 in “ Journal of dermatological science ”
    Sun Young Yoon, Jung Ah Yoon, Seong Jin Jo, Changyong Shin, Jong Yeon Shin, Jong‐Il Kim, Oh Sang Kwon, Kyu Han Kim
    Image of study
    TLDR Placental growth factor may help treat hair loss.
    The study investigated the role of placental growth factor (PlGF) in hair growth by analyzing gene expression in dermal papilla cells (DPCs) from human hair follicles. PlGF expression decreased with cell subculture, but its application enhanced hair shaft elongation in ex vivo cultures and accelerated hair follicle growth in an in vivo depilation model. PlGF promoted cell survival by increasing phosphorylated ERK, cyclin D1, phosphorylated Akt, and Bcl2 levels. The findings suggested that PlGF could be a potential therapeutic target for treating alopecia.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 12 results

      community This guy claims stem cells fixed his balding

      in Is this regrowth?  301 upvotes 1 year ago
      A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  6 upvotes 4 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community Injecting stomach fat into the scalp could cure baldness in just six months

      in Update  114 upvotes 6 years ago
      A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

      community Which mesotherapy should I choose?

      in Research/Science  1 upvotes 7 months ago
      A user is considering adding PRP and mesotherapy to their hair loss treatment and is deciding between two options: Promoitalia, which contains Phosphatidic acid, Riboflavin, and Superoxide dismutase, and the more expensive Melsmon, a human placenta derivative. They seek advice on which option to choose based on effectiveness and scientific backing.

    Similar Research

    5 / 1000+ results