Topical Minoxidil Counteracts Stress-Induced Hair Growth Inhibition in Mice

    September 2003 in “ Experimental Dermatology ”
    Petra C. Arck, Bori Handjiski, Eva M.J. Peters … Ralf Paus
    Studysummary In this study on a murine model, researchers observed that a 5% minoxidil solution reduced stress-induced changes in hair growth, suggesting its potential for managing stress-related hair loss in humans.
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    Research cited in this study 15

    1. Indications for a Brain-Hair Follicle Axis: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P The FASEB Journal · 2001
    2. Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin and Hair Growth Modulation by Neuropeptides Journal of Investigative Dermatology · 2001
    3. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    4. Diffuse Hair Loss: Causes, Diagnosis, and Treatment International Journal of Dermatology · 1999
    5. Hair Follicle Elongation in Organ Culture of Skin from Newborn and Adult Mice Journal of Dermatological Science · 1998
    6. A Simple Immunofluorescence Technique for Simultaneous Visualization of Mast Cells and Nerve Fibers Reveals Selectivity and Hair Cycle-Dependent Changes in Mast Cell-Nerve Fiber Contacts in Murine Skin Archives of Dermatological Research · 1997
    7. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997
    8. Neural Mechanisms of Hair Growth Control Journal of Investigative Dermatology Symposium Proceedings · 1997
    9. Whole Hair Follicle Culture Dermatologic clinics · 1996
    10. Hair Follicle Stem Cells: Their Location, Role in Hair Cycle, and Involvement in Skin Tumor Formation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    11. Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration Journal of Investigative Dermatology · 1992
    12. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989
    13. Effect of Minoxidil on Pre- and Postconfluent Keratinocytes Journal of The American Academy of Dermatology · 1987
    14. Psychosomatic Concepts in Dermatology Archives of dermatology · 1983
    15. Reversal of Baldness in Patient Receiving Minoxidil for Hypertension The New England Journal of Medicine · 1980

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    8. Topical Minoxidil Counteracts Stress-Induced Hair Growth Inhibition in Mice Experimental Dermatology · 2003
    9. Differences in Activity of Minoxidil and Cyclosporin A on Hair Growth in Nude and Normal Mice: Comparisons of In Vivo and In Vitro Studies PubMed · 1990