Pretreatment of Epidermal Growth Factor Promotes Primary Hair Recovery via the Dystrophic Anagen Pathway After Chemotherapy-Induced Alopecia
May 2013
in “
Experimental Dermatology
”
TLDR Epidermal growth factor helps hair recover after chemotherapy.
The study explored the impact of epidermal growth factor (EGF) on chemotherapy-induced alopecia using a C57BL/6 mouse model. EGF was applied topically to induce a protective catagen-like stage in hair follicles, reducing apoptosis and delaying alopecia progression. The treatment promoted hair recovery via the dystrophic anagen pathway, suggesting EGF as a potential strategy to mitigate chemotherapy-induced hair loss and enhance regrowth. The study did not specify the number of participants, which is crucial for evaluating the robustness of the results.
