Prostate Cancer Prevention

September 2007 in “ Cancer ”

Neil Fleshner, Alexandre R. Zlotta

5-alpha reductase inhibitors finasteride Propecia

TLDR Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Prostate cancer was the most common male malignancy and a leading cause of cancer death among men in the West. The article reviewed various prevention strategies, including dietary fat reduction, supplementation with vitamins D and E, selenium, soy, green tea, and lycopene-rich products. It also examined pharmacological interventions like cyclo-oxygenase inhibitors, antiestrogens, and 5-alpha reductase inhibitors, highlighting the Prostate Cancer Prevention Trial and the controversy over higher-grade cancers with finasteride. The article noted that prostate cancer prevention was extensively researched, with definitive answers from pivotal phase 3 trials expected within 2 to 7 years.

View this study on acsjournals.onlinelibrary.wiley.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 1 year ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community If you're sitting there wondering, "I'm losing my hair, what do I do?" then read my advice here. I've been fighting the fight for 7 years, with great success. (pictures included)

in Question 109 upvotes 11 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community Hey guys I’m in desperate need for opinions from long term finasteride users

in Finasteride/Dutasteride 25 upvotes 2 years ago

Whether taking finasteride and dutasteride can cause penile shrinkage, with long-term users providing their personal experiences.

community Ultimate DHT/finasteride microdosing graph to replace the commonly one referenced on forums

in Finasteride/Dutasteride 207 upvotes 4 years ago

Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.