Prostate Cancer Prevention

September 2007 in “ Cancer ”

Neil Fleshner, Alexandre R. Zlotta

5-alpha reductase inhibitors finasteride Propecia

TLDR Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Prostate cancer was the most common male malignancy and a leading cause of cancer death among men in the West. The article reviewed various prevention strategies, including dietary fat reduction, supplementation with vitamins D and E, selenium, soy, green tea, and lycopene-rich products. It also examined pharmacological interventions like cyclo-oxygenase inhibitors, antiestrogens, and 5-alpha reductase inhibitors, highlighting the Prostate Cancer Prevention Trial and the controversy over higher-grade cancers with finasteride. The article noted that prostate cancer prevention was extensively researched, with definitive answers from pivotal phase 3 trials expected within 2 to 7 years.

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