Male Pattern Baldness in Relation to Prostate Cancer-Specific Mortality: A Prospective Analysis in the NHANES I Epidemiologic Follow-Up Study

January 2016 in “ American Journal of Epidemiology ”

Cindy Ke Zhou, Paul H. Levine, Sean D. Cleary, Heather J. Hoffman, Barry I. Graubard, Michael B. Cook

male pattern baldness prostate cancer baldness pathophysiology MPB

TLDR Men with male pattern baldness have a higher risk of dying from prostate cancer.

The study analyzed data from 4,316 men over a median follow-up period of 21 years and found that male pattern baldness was associated with a significantly increased risk of prostate cancer-specific mortality. Any degree of baldness was linked to a 56% higher risk, while moderate baldness was associated with an 83% higher risk of fatal prostate cancer. The study did not find a significant link between baldness and all-cause mortality. These results suggest a potential shared pathophysiology between male pattern baldness and prostate cancer, but baldness should not be used as a criterion for prostate cancer screening. Further research is needed to confirm these findings and assess any additional predictive value.

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Relationship Between Male Pattern Baldness and the Risk of Aggressive Prostate Cancer: An Analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

research Relationship Between Male Pattern Baldness and the Risk of Aggressive Prostate Cancer: An Analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

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Early balding at 40 increases prostate cancer risk.

research Male Pattern Baldness and Its Association with Coronary Heart Disease: A Meta-Analysis

26 citations, January 2013 in “BMJ Open”

Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.

research Male Pattern Baldness and the Risk of Prostate Cancer

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Hair loss linked to higher heart disease risk in both men and women.

research Androgenic Alopecia Is Not Useful as an Indicator of Men at High Risk of Prostate Cancer

28 citations, June 2010 in “European Journal of Cancer”

Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.

research Male Pattern Baldness and Prostate Cancer Risk in a Population-Based Case-Control Study

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Men who start losing hair at age 30 may have a lower risk of prostate cancer.

research Baldness, Benign Prostate Hyperplasia, Prostate Cancer, and Androgen Levels

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The study found no link between baldness patterns and androgen levels in men with benign prostate enlargement or prostate cancer.

research Androgenetic Alopecia and Prostate Cancer: Findings from an Australian Case-Control Study

21 citations, June 2002 in “PubMed”

The conclusion is that there might be a link between certain types of baldness and prostate cancer, which could be due to shared hormonal pathways.

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research The Association of Male Pattern Baldness and Risk of Cancer and High-Grade Disease Among Men Presenting for Prostate Biopsy

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research Obstructive Sleep Apnea, Low Transferrin Saturation Levels, and Male-Pattern Baldness

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