The Association of Male Pattern Baldness and Risk of Cancer and High-Grade Disease Among Men Presenting for Prostate Biopsy

    Al Edwan G, Bimal Bhindi, David Margel, Karen Chadwick, Antonio Finelli, Alexandre Zlotta, John Trachtenberg, Neil Fleshner
    Image of study
    TLDR Men with more advanced male pattern baldness have a higher risk of prostate cancer and more severe disease.
    In a study of 394 men undergoing prostate biopsy at the Princess Margaret Cancer Centre, researchers found that male pattern baldness (MPB) was associated with an increased risk of prostate cancer (PCa) and high-grade disease. Using the modified Norwood classification system to assess MPB, the study revealed a dose-effect relationship where higher Norwood patterns correlated with higher risks. Men with Norwood scale 3 and 4 had an increased risk for cancer, and those with Norwood pattern 4 had an increased risk for high-grade disease. The study concluded that MPB is a strong and independent risk factor for both cancer and high-grade disease in this population, suggesting the need for further research and potential integration into clinical decision-making processes.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 1 month ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  326 upvotes 9 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

      community Fevipiprant 2019!

       17 upvotes 8 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community I'm gonna be bald by 20 and I'm not even exagerrating. Wtf do I even do?

      in Chat  77 upvotes 1 year ago
      A 16-year-old is experiencing early male pattern baldness and is considering using Minoxidil now and Finasteride after turning 18. Another user shared a positive experience with topical Minoxidil and Finasteride, noting improvement in hair thickness and no side effects.

      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 11 months ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

    Similar Research

    5 / 1000+ results