14 citations
,
September 2010 in “Annals of Plastic Surgery” This article reviews recent advancements in understanding hair follicle biology, with a focus on the potential for gene therapy in treating alopecia, but it reports no new research findings.
69 citations
,
April 2010 in “British Journal of Dermatology” This study found a significant association between androgenetic alopecia and metabolic syndrome, highlighting high-density lipoprotein cholesterol as a particularly important factor.
21 citations
,
October 2009 in “Molecular Biology Reports” 8 citations
,
February 2009 in “Journal of Dermatological Science” Targeting androgen receptors with antiandrogen oligonucleotides could effectively treat hair loss.
209 citations
,
September 2008 in “Dermatologic Therapy” This review discusses the role of androgens in hair follicle regulation and suggests that a better understanding could enhance treatments for conditions like hirsutism and alopecia, but does not present new findings.
39 citations
,
January 2008 in “Journal of Endocrinology” This study found that in androgenetic alopecia, reduced stem cell factor production by dermal papilla cells may lead to decreased pigmentation in hair follicles.
17 citations
,
January 2007 in “Annals of Medicine” This review discusses advancements and challenges in cutaneous gene therapy using direct and indirect techniques, noting that while clinical translation has begun, further developments are essential for progress.
112 citations
,
October 2005 in “Mayo Clinic Proceedings” This article reviews the clinical, psychological, and management aspects of androgenetic alopecia in men, stating that it can be effectively managed by generalist clinicians with pharmacotherapy and surgical advancements.
34 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses advancements in gene delivery to hair follicles and suggests potential gene therapy applications for treating hair loss, but it reports no new experimental results.
78 citations
,
August 2002 in “Experimental Dermatology” This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.
54 citations
,
May 1998 in “Urology” This study demonstrates that patients with benign prostatic hyperplasia have a higher severity and frequency of male pattern baldness compared to a control group.
227 citations
,
January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.