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    Glossary miR-221

    regulates gene expression and impacts hair follicle activity

    miR-221 is a type of microRNA, which are small, non-coding RNA molecules that play a role in regulating gene expression. Specifically, miR-221 has been found to influence cell cycle progression and has been implicated in various biological processes, including cancer development and hair growth regulation. In the context of hair, miR-221 can affect the activity of hair follicle cells, potentially contributing to conditions like alopecia.

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    1. The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia International Journal of Biological Sciences · 2023 · 2 citations
    2. Ar/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia Social Science Research Network · 2022
    3. Hair shaft miRNA‐221 levels as a new tumor marker of malignant melanoma Journal of dermatology · 2014 · 7 citations
    4. Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method British Journal of Dermatology · 2011 · 29 citations
    5. Integrated miRNA and mRNA Analysis Provides New Insight into Mechanism of dermal papilla in Androgenetic Alopecia Research Square (Research Square) · 2024
    6. The Pathogenesis and Treatment Progress of Androgenic Alopecia Journal of Biosciences and Medicines · 2024
    7. Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022 · 21 citations
    8. Hair Follicle-Related MicroRNA-34a Serum Expression and rs2666433A/G Variant in Patients with Alopecia: A Cross-Sectional Analysis Biomolecules · 2022 · 3 citations
    9. Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes Scientific Reports · 2017 · 54 citations
    10. Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p 2025
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