Prostate Cancer Incidence Among Finasteride and Alpha-Blocker Users in the Finnish Prostate Cancer Screening Trial

    August 2009 in “ British Journal of Cancer ”
    Teemu J. Murtola, Teuvo L.J. Tammela, Liisa Määttänen, Martti Ala-Opas, Ulf-Håkan Stenman, Anssi Auvinen
    Image of study
    TLDR Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.
    In an observational cohort study within the Finnish Prostate Cancer Screening Trial involving 23,320 men, researchers found that finasteride users had a decreased incidence of low-grade prostate tumors (Gleason 2-6) but no significant change in the incidence of high-grade tumors (Gleason 7-10) compared to non-users. Alpha-blocker users showed no significant change in overall prostate cancer risk but had a decreased incidence of high-grade tumors. The study concluded that finasteride may have a protective effect against low-grade prostate cancer in men treated for benign prostatic hyperplasia (BPH). However, the study had limitations, including a small number of advanced cancer cases and incomplete data on risk factors and finasteride use duration. The study suggests further research is needed to assess finasteride's potential to reduce prostate cancer mortality.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community My mum is mad annoying about Fin.

      in Chat  245 upvotes 6 months ago
      A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.

      community Update: 4 Month progress on Fin/Min plus dermaroller

      in Progress Pictures  559 upvotes 10 months ago
      A user shared a 4-month update on their hair regrowth progress using finasteride, minoxidil, a dermaroller, ketoconazole shampoo, multivitamins, and biotin, and received positive reactions and inquiries from others. They also mentioned lifestyle changes such as quitting creatine, alcohol, and smoking, which may have contributed to their success.

      community Can hair thinning be reversed?

      in Finasteride/Dutasteride  36 upvotes 1 year ago
      The conversation is about the effectiveness of Dutasteride (Dut) and Minoxidil (Min) in reversing hair thinning. The user has been using Dut for 3 months and Min for a couple of years, and while hair fall has reduced, thinning continues. Other users suggest that Dut can reverse hair thinning over time, possibly beyond a year, and the outcome depends on individual body reactions and the degree of hair miniaturization.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 7 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

    Similar Research

    5 / 1000+ results