Cardiovascular Effects of Hormone Therapy for Prostate Cancer
July 2015
in “
Drug Healthcare and Patient Safety
”
TLDR Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
The document reviewed the cardiovascular effects of hormone therapy for prostate cancer, highlighting that androgen deprivation therapy (ADT) was associated with increased risks of cardiovascular diseases, including myocardial infarction, stroke, and diabetes. Multiple studies indicated that men undergoing ADT had higher incidences of cardiovascular events compared to those not receiving such therapy. The review also discussed the potential benefits of alternative treatments, such as GnRH antagonists, which might pose fewer cardiovascular risks. Additionally, lifestyle interventions, including exercise and diet, were suggested to mitigate some adverse effects of ADT. The findings underscored the need for careful cardiovascular monitoring and management in prostate cancer patients undergoing hormone therapy.