TLDR Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
The document reviewed the cardiovascular effects of hormone therapy for prostate cancer, highlighting that androgen deprivation therapy (ADT) was associated with increased risks of cardiovascular diseases, including myocardial infarction, stroke, and diabetes. Multiple studies indicated that men undergoing ADT had higher incidences of cardiovascular events compared to those not receiving such therapy. The review also discussed the potential benefits of alternative treatments, such as GnRH antagonists, which might pose fewer cardiovascular risks. Additionally, lifestyle interventions, including exercise and diet, were suggested to mitigate some adverse effects of ADT. The findings underscored the need for careful cardiovascular monitoring and management in prostate cancer patients undergoing hormone therapy.
104 citations
,
March 2014 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” DHT may increase the risk of heart disease and death in elderly men.
35 citations
,
January 2012 in “The Journal of Sexual Medicine” Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
6 citations
,
May 2008 in “Current Opinion in Oncology” 2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.
August 2008 in “Current Opinion in Internal Medicine” In 2007, prostate cancer research improved understanding of risk, diagnosis, and treatment, but also showed heart risks with certain therapies and the need for personalized care.
17 citations
,
January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
4 citations
,
June 2023 in “Frontiers in Aging” Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
