Animal and In Vitro Models for the Study of Hair Follicles

    June 2003 in “ Journal of Investigative Dermatology Symposium Proceedings ”
    Valerie A. Randall, John P. Sundberg, Michael P. Philpott
    TLDR Understanding hair follicles through various models can help develop new treatments for hair disorders.
    The document reviewed various in vitro and in vivo models used to study hair follicles, focusing on their role in understanding hair growth and disorders like androgenetic alopecia and alopecia areata. It discussed the use of genetically modified animals and cell cultures, such as dermal papilla cells, to explore the biological and biochemical mechanisms of hair follicles. These models provided insights into the effects of androgens and growth factors on hair growth, highlighting the importance of synthesizing information from different models due to the unique characteristics of human hair growth. The research aimed to facilitate a better understanding of hair follicle function and aid in developing novel treatments for hair disorders.
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