Animal Models for Male Pattern (Androgenetic) Alopecia
June 2001
in “
PubMed
”
TLDR The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
The review from 22 years ago discussed the use of animal models in studying male pattern (androgenetic) alopecia. The stump-tailed macaque (Macaca arctoides) was identified as a suitable biological model for human androgenetic alopecia, although its use was limited due to expense, danger, and low availability. Rodent models, including testosterone induced alopecia and various xenograft approaches, were considered promising for providing fundamental information on normal and abnormal hair growth. These models were also seen as useful for developing new therapies to treat hair loss.
