Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth

    August 2020 in “ International Journal of Molecular Sciences ”
    Kyung Eun Ku, Nahyun Choi, Jong Hwan Sung
    Studysummary This study found that Rab27a and Rab27b play opposite roles in hair growth, with Rab27a knockdown suppressing and Rab27b knockdown promoting hair growth in models.
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    Research cited in this study 9

    1. HB-EGF Improves the Hair Regenerative Potential of Adipose-Derived Stem Cells via ROS Generation and Hck Phosphorylation International Journal of Molecular Sciences · 2019
    2. Hypoxia Improves Hair Inductivity of Dermal Papilla Cells via Nuclear NADPH Oxidase 4-Mediated Reactive Oxygen Species Generation British Journal of Dermatology · 2019
    3. Platelet-Rich Plasma: The Ultimate Secret for Youthful Skin Elixir and Hair Growth Triggering Journal of Cosmetic Dermatology · 2017
    4. Hair Transplantation Update Seminars in Cutaneous Medicine and Surgery · 2015
    5. Platelet-Rich Plasma for Androgenetic Alopecia Dermatologic Surgery · 2014
    6. Aging of the Hair Follicle Pigmentation System International journal of trichology · 2009
    7. The Chemotactic Effect of a Dermal Papilla Cell-Derived Factor on Outer Root Sheath Cells Journal of Dermatological Science · 2001
    8. Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    9. Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells Archives of Dermatological Research · 1993

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