Does D Matter? The Role of Vitamin D in Hair Disorders and Hair Follicle Cycling

February 2010 in “ Dermatology Online Journal ”

Karrie T. Amor, Rashid M. Rashid, Paradi Mirmirani

vitamin D vitamin D receptor VDR anagen phase alopecia male pattern baldness hair follicle cycling

TLDR Vitamin D may help treat hair disorders.

The document reviewed the role of vitamin D and its receptor (VDR) in hair disorders and hair follicle cycling, emphasizing that VDR, independent of vitamin D, was crucial for initiating the anagen phase. While animal models showed that VDR absence led to alopecia, human studies were limited and inconclusive, with a study of 296 men finding no link between male pattern baldness and vitamin D levels. The review suggested that treatments upregulating VDR could potentially address hair disorders and called for more research, particularly on vitamin D's role and optimal levels for treatment.

View this study on escholarship.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 5 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Why are there no studies on Topical Vitamin D3 for AGA?

in Research/Science 10 upvotes 1 year ago

Topical Vitamin D3 may stimulate hair growth and has been used for Alopecia Areata. There is a question about the lack of research on its use for Androgenetic Alopecia (AGA).

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Is Vitamin D the cause of my baldness or slow regrowth?

in Is this regrowth? 1 upvotes 3 weeks ago

The conversation discusses hair loss treatments, including oral finasteride, topical minoxidil, and microneedling, and the potential impact of Vitamin D and folic acid deficiencies on hair regrowth. It suggests that while male pattern baldness is the primary cause, addressing vitamin deficiencies may aid in improving regrowth.

community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 2 months ago

Genetic differences in hair follicles affect hair loss patterns. Treatments discussed include finasteride, dutasteride, minoxidil, and RU58841.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 64 upvotes 1 year ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

Related Research

4 / 4 results

research Blockade of S100A3 Activity Inhibits Murine Hair Growth

1 citations , January 2015 in “Genetics and Molecular Research”

Stopping S100A3 activity slows down hair growth in mice.

research Alopecia

January 2002 in “Journal of the Korean Medical Association”

Recent research has provided important insights into hair growth and hair loss treatments.

research Towards a Molecular Understanding of Hair Loss and Its Treatment

236 citations , July 2001 in “Trends in Molecular Medicine”

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

research Treatment of Hair Loss

370 citations , September 1999 in “The New England Journal of Medicine”

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.