The 'DHT itch' is real - notes from a casual bodybuilder Chat 9/18/2024
The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.
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5 / 5 resultscommunity Can testosterone alone cause hair loss even after nuking DHT?
Testosterone can still cause hair loss even when DHT is blocked by dutasteride, especially if hair follicles are sensitive. Topical treatments like RU58841 or pyrilutamide may help, but their long-term effectiveness is uncertain compared to dutasteride.
community Is DHT actually the cause of male pattern hair loss or just a correlating factor? Why I think the research is more complicated than we're told and why I've been looking into GHK-Cu
DHT is not the only cause of male pattern hair loss; genetic sensitivity, inflammation, and fibrosis also contribute. GHK-Cu, a copper peptide, is being explored as an alternative treatment to finasteride and minoxidil, showing potential in improving follicle health.
community The mechanism of androgenic alopecia
DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.
community Dht kills hair, but no one says why?
DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.
community Testosterone in Reference Range Doesn't Cause Hair Loss
Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.
Related Research
6 / 6 results
research Alopecia androgénica femenina: nuevos factores fisiopatológicos y futuras tendencias para un abordaje clínico más integral
New factors in female hair loss include genetics, hormones, stress, and inflammation; future treatments should also focus on these areas and consider the patient's emotional well-being.
research Androgen effects on the skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth
This review suggests that hair loss involves a complex interplay of androgen signaling with various regenerative and inflammatory pathways, challenging the view of dihydrotestosterone as the sole cause.
research The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth
This narrative literature review by LUSTRAO examines the complex biological mechanisms influencing hair growth and loss, highlighting that androgen signalling, while significant, works within a network involving regenerative, inflammatory, and vascular processes, without establishing it as the sole explanation for conditions like androgenetic alopecia.
research The promotion of hair regrowth by topical application of a Perilla frutescens extract through increased cell viability and antagonism of testosterone and dihydrotestosterone
This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
research Male pattern hair loss: current understanding
Genetics and hormones cause hair loss; finasteride treats it safely.