Acne and Systemic Diseases
November 2015
in “
European medical journal
”
acne hypovitaminosis congenital adrenal hyperplasia seborrhoea-acne-hirsutism-androgenetic alopecia syndrome polycystic ovary syndrome hyperandrogenaemia insulin resistance acanthosis nigricans syndrome Apert syndrome synovitis-acne-pustulosis-hyperostosis-osteitis syndrome pyogenic arthritis pyoderma gangrenosum acne syndrome metabolic syndromes Behçet’s syndrome vitamin deficiency CAH SAHA syndrome PCOS high androgen levels AN syndrome SAPHO syndrome Behçet’s disease
TLDR Acne is common and can be linked to various systemic health conditions and syndromes.
The 2015 study "Acne and Systemic Diseases" by Tugba Kevser Uzuncakmak, Ayse Serap Karadag, and Necmettin Akdeniz from Istanbul Medeniyet University School of Medicine, found that acne is a complex, chronic disease affecting approximately 85% of adolescents and 3% of adults. It is not life-threatening but is associated with a lower quality of life and psychological depression. The study also found that acne can be associated with hypovitaminosis and may be part of systemic syndromes such as congenital adrenal hyperplasia, seborrhoea-acne-hirsutism-androgenetic alopecia syndrome, polycystic ovary syndrome, hyperandrogenaemia, insulin resistance, and acanthosis nigricans syndrome, Apert syndrome, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome, pyogenic arthritis, pyoderma gangrenosum, and acne syndrome, metabolic syndromes, and Behçet’s syndrome. These syndromes should be ruled out in patients with severe and persistent acne.
