Acne and Systemic Diseases

    November 2015 in “ European medical journal ”
    Tuğba Kevser Uzunçakmak, Ayşe Serap Karadağ, Necmettın Akdeniz
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    TLDR Acne is common and can be linked to various systemic health conditions and syndromes.
    The 2015 study "Acne and Systemic Diseases" by Tugba Kevser Uzuncakmak, Ayse Serap Karadag, and Necmettin Akdeniz from Istanbul Medeniyet University School of Medicine, found that acne is a complex, chronic disease affecting approximately 85% of adolescents and 3% of adults. It is not life-threatening but is associated with a lower quality of life and psychological depression. The study also found that acne can be associated with hypovitaminosis and may be part of systemic syndromes such as congenital adrenal hyperplasia, seborrhoea-acne-hirsutism-androgenetic alopecia syndrome, polycystic ovary syndrome, hyperandrogenaemia, insulin resistance, and acanthosis nigricans syndrome, Apert syndrome, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome, pyogenic arthritis, pyoderma gangrenosum, and acne syndrome, metabolic syndromes, and Behçet’s syndrome. These syndromes should be ruled out in patients with severe and persistent acne.
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