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    Glossary SAPHO syndrome

    rare disorder causing joint inflammation and severe skin conditions

    SAPHO syndrome is a rare, chronic disorder that stands for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis. It primarily affects the skin and bones, leading to painful inflammation in the joints and skin conditions like severe acne and pustules. The exact cause is unknown, but it is believed to involve both genetic and environmental factors.

    Research 10 of 76

    1. [Methotrexate to treat SAPHO syndrome with keloidal scars]. PubMed · 2011 · 10 citations
    2. S4890 Infliximab-Induced Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis Syndrome The American Journal of Gastroenterology · 2025
    3. Acne-Associated Syndromes Springer eBooks · 2019
    4. Diseases associated with hidranitis suppurativa: part 2 of a series on hidradenitis Dermatology Online Journal · 2013 · 78 citations
    5. Acne and Systemic Disease Medical Clinics of North America · 2009 · 76 citations
    6. Acne as a chronic systemic disease Clinics in Dermatology · 2013 · 71 citations
    7. Difficult and rare forms of acne Clinics in Dermatology · 2016 · 18 citations
    8. Acne and Systemic Diseases European medical journal · 2015 · 1 citations
    9. Acne-Associated Syndromes InTech eBooks · 2017 · 1 citations
    10. Acne-associated syndromes: models for better understanding of acne pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010 · 99 citations
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