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GlossarySAPHO syndrome

rare disorder causing joint inflammation and severe skin conditions

SAPHO syndrome is a rare, chronic disorder that stands for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis. It primarily affects the skin and bones, leading to painful inflammation in the joints and skin conditions like severe acne and pustules. The exact cause is unknown, but it is believed to involve both genetic and environmental factors.

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research Methotrexate to Treat SAPHO Syndrome with Keloidal Scars

10 citations , December 2011 in “PubMed”

Methotrexate effectively managed SAPHO syndrome symptoms when other treatments failed.

research Acne-Associated Syndromes

January 2019 in “Springer eBooks”

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

research Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis

January 2012 in “Yearbook of Dermatology and Dermatologic Surgery”

Studying acne-related syndromes helps us understand acne causes and can lead to new treatments.

research Diseases Associated With Hidradenitis Suppurativa: Part 2 of a Series on Hidradenitis

78 citations , January 2013 in “Dermatology Online Journal”

Hidradenitis suppurativa is linked to various diseases like obesity, depression, arthritis, and Crohn's disease, but often occurs alone.

research Acne and Systemic Disease

76 citations , November 2009 in “Medical Clinics of North America”

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

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