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    GlossaryChronic Recurrent Multifocal Osteomyelitis

    rare, non-infectious bone inflammation causing recurring pain in multiple sites

    Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare, autoinflammatory bone disorder characterized by recurrent episodes of bone pain and inflammation in multiple locations throughout the body. Unlike typical osteomyelitis, CRMO is not caused by an infection but rather by an abnormal immune response, and it often requires long-term management with anti-inflammatory medications.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

    Research

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      Acne and Systemic Disease

      research Acne and Systemic Disease

      76 citations , November 2009 in “Medical Clinics of North America”
      Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
      Hormone Therapy in Acne

      research Hormone Therapy in Acne

      24 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”
      Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
      Acne-Associated Syndromes

      research Acne-Associated Syndromes

      January 2019 in “Springer eBooks”
      Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
      Difficult and Rare Forms of Acne

      research Difficult and Rare Forms of Acne

      18 citations , October 2016 in “Clinics in Dermatology”
      The document talks about hard-to-treat and rare acne types, their connection with other health issues, the importance of correct diagnosis, and the challenges in managing them.

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      community 2 years of treatment with fin, dut and oral minoxidil

      in Progress Pictures  6 upvotes 1 month ago
      The user experienced chronic telogen effluvium and mild male pattern baldness, treated with finasteride, oral minoxidil, and later switched to dutasteride, which stopped excessive hair shedding. Other treatments like low-level laser therapy, hair loss shampoos (except ketoconazole), and supplements were ineffective.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  416 upvotes 10 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community On Dutasteride 0.5mg ED for almost 2 years. Increasingly shedding hair for more than 5 months.

      in Finasteride/Dutasteride  8 upvotes 8 months ago
      The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.

      community I have a theory about hair loss

      in Treatment 1 month ago
      Hair loss is often linked to inflammation and DHT, with treatments like finasteride, dutasteride, and minoxidil being effective for many. Natural remedies like turmeric and oils are discussed, but medications are generally seen as more reliable for managing genetic hair loss.