Dermatologic Manifestations in Patients with Polycystic Ovary Syndrome: Their Prevalence and Assessment in Relation to Hormonal and Metabolic Changes

    November 2020 in “ ALEXMED ePosters (Online) ”
    Hend Hassan Gaber, Sami Abdelhamid Abuzeid, Nouran Abdelaziz Abukhedr, sherif gaafar, Maha Bondok
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    TLDR People with PCOS often have skin problems like excessive hair growth, hair loss, acne, and dark patches, which are linked to hormonal and metabolic imbalances.
    The study, conducted on 53 patients diagnosed with Polycystic ovary syndrome (PCOS) aged 20-40 years and 50 non-PCOS controls of the same age group, aimed to detect the prevalence of dermatologic manifestations among an Egyptian PCOS cohort and study the correlation between these manifestations and the underlying hormonal and metabolic changes. The prevalence of hirsutism was found to be 49%, androgenetic alopecia (AGA) 43.3%, acne 39.6%, and acanthosis nigricans 32% among the PCOS patients. Hirsutism in PCOS patients was associated with higher levels of total and free testosterone. However, acne and AGA in PCOS patients did not seem to be influenced by serum androgen levels, HOMA-IR, or anthropometric measures. Acanthosis nigricans was more related to the metabolic disorder rather than to hyperandrogenism.
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