Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome

February 2021 in “ JCPSP. Journal of the College of Physicians & Surgeons Pakistan ”

Fatima Sheikh, Ghazala Butt, Rukhsha Hafeez, Aiman Maqsood, Faria Altaf, Ijaz Hussain

androgenetic alopecia metabolic syndrome serum triglycerides waist circumference cardiovascular disease AGA

TLDR Early-onset hair loss in young males is linked to a higher risk of metabolic syndrome.

The study conducted at Mayo Hospital Lahore with 202 participants found a significant association between early-onset androgenetic alopecia (AGA) and metabolic syndrome in young males aged 20-36. AGA patients had a fourfold increased risk of metabolic syndrome compared to controls, with notable differences in serum triglycerides and waist circumference. The study suggested that AGA could be a risk factor for cardiovascular disease and recommended early screening for metabolic syndrome in AGA patients. Despite acknowledging discrepancies and the need for further research with larger populations, the study concluded that AGA is significantly associated with metabolic syndrome.

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Research cited in this study

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Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.

research Relation of Urinary Stone Disease with Androgenetic Alopecia and Serum Testosterone Levels

6 citations, May 2016 in “Urolithiasis”

Balding and low testosterone increase risk of urinary stones.

research Metabolic Syndrome in Androgenic Alopecia

16 citations, January 2016 in “Indian Journal of Dermatology, Venereology and Leprology”

Metabolic syndrome is more common in people with early-onset androgenic alopecia.

research Androgenetic Alopecia as an Indicator of Metabolic Syndrome and Cardiovascular Risk

13 citations, November 2015 in “Blood Pressure”

Hair loss may indicate higher heart risk and metabolic issues.

research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?

24 citations, January 2015 in “International Journal of Trichology”

Early balding in young Indian men may indicate a higher risk of metabolic syndrome and potential heart disease.

research Alopecia and Its Association with Coronary Heart Disease and Cardiovascular Risk Factors: A Meta-Analysis

48 citations, October 2014 in “International Journal of Cardiology”

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

34 citations, July 2014 in “Indian Dermatology Online Journal”

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

research Association of Premature Androgenetic Alopecia and Metabolic Syndrome in a Young Indian Population

16 citations, April 2014 in “International Journal of Trichology”

Early hair loss links to metabolic issues in young Indian men.

research Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome in Thai Men: A Case-Control Study

8 citations, August 2013 in “PubMed”

research Metabolic Syndrome and Skin: Psoriasis and Beyond

50 citations, January 2013 in “Indian Journal of Dermatology”

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

research The Association of Insulin Resistance and Metabolic Syndrome in Early Androgenetic Alopecia

18 citations, December 2010 in “PubMed”

People with early hair loss may have higher insulin levels and a greater chance of developing metabolic syndrome.

research Association of Androgenetic Alopecia With Smoking and Its Prevalence Among Asian Men

91 citations, November 2007 in “Archives of Dermatology”

Smoking linked to hair loss in Asian men.

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

56 citations, June 2001 in “European journal of cardiovascular prevention & rehabilitation”

Early balding linked to higher heart disease risk.

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research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?

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Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome

Research cited in this study

research Association of Androgenetic Alopecia with Metabolic Syndrome: A Case-Control Study on 100 Patients in a Tertiary Care Hospital in South India

research Association of Androgenic Alopecia with Metabolic Syndrome

research A Comparison of the Hormonal Profile of Early Androgenetic Alopecia in Men With the Phenotypic Equivalent of Polycystic Ovarian Syndrome in Women

research Relation of Urinary Stone Disease with Androgenetic Alopecia and Serum Testosterone Levels

research Metabolic Syndrome in Androgenic Alopecia

research Androgenetic Alopecia as an Indicator of Metabolic Syndrome and Cardiovascular Risk

research Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients?

research Alopecia and Its Association with Coronary Heart Disease and Cardiovascular Risk Factors: A Meta-Analysis

research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study

research Association of Premature Androgenetic Alopecia and Metabolic Syndrome in a Young Indian Population

research Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome in Thai Men: A Case-Control Study

research Metabolic Syndrome and Skin: Psoriasis and Beyond

research The Association of Insulin Resistance and Metabolic Syndrome in Early Androgenetic Alopecia

research Association of Androgenetic Alopecia With Smoking and Its Prevalence Among Asian Men

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

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community Anyone else growing tired of the finasteride wars?

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community I am a dermatologist with a clinical interest in alopecia. AMA

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