The Prevalence of Metabolic Syndrome in Male Patients of Early Onset Androgenic Alopecia Compared to Age-Matched Controls

December 2021 in “ International Journal of Research in Dermatology ”

Nitin K. Chaudhari, Chandrakant B. Poulkar, Swapna S Khatu, Gaurav H. Khandait, Rajvardhan Bagane, Arun M. Patokar, Chinmay M. Ratkanthiwar, Supriya S. Pathade

metabolic syndrome androgenic alopecia waist circumference diastolic blood pressure serum triglycerides serum high-density lipoproteins cardiovascular mortality male pattern baldness waist size blood pressure triglycerides HDL heart disease

TLDR Men with early-onset hair loss have a higher risk of metabolic syndrome.

This study investigated the prevalence of metabolic syndrome in 100 male patients with early-onset androgenic alopecia compared to 100 age-matched controls, all aged 20-35 years. The results showed that metabolic syndrome was significantly more prevalent in patients with androgenic alopecia (48%) than in controls (18%, p < 0.001). Additionally, androgenic alopecia patients had higher rates of increased waist circumference (76% vs. 28%, p < 0.0001), increased diastolic blood pressure (32% vs. 12%, p = 0.007), increased serum triglycerides (46% vs. 24%, p = 0.0011), and decreased serum high-density lipoproteins (36% vs. 18%, p = 0.0042). The study concludes that early screening for metabolic syndrome in patients with androgenic alopecia could help reduce cardiovascular mortality.

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