A Study on the Clinical, Biochemical, and Hormonal Profile of Polycystic Ovary Syndrome Patients Attending a Tertiary Care Hospital
TLDR The study concluded that a higher waist-hip ratio significantly increases the risk of metabolic syndrome in women with PCOS.
Between January 2014 and July 2015, a study involving 100 patients with polycystic ovary syndrome (PCOS) was conducted to examine their clinical, biochemical, and hormonal profiles. The study found a 6.3% prevalence of PCOS among gynecology outpatients and 37.14% among infertile women. The most common symptoms were menstrual irregularity (31%) and infertility (23%), with a significant correlation between menstrual irregularities and elevated levels of luteinizing hormone (LH) and an elevated LH to follicle-stimulating hormone (FSH) ratio. Additionally, 21.3% of the participants had metabolic syndrome, with a 21-fold increased risk associated with a higher waist-hip ratio (WHR). The majority of PCOS patients were hirsute with central obesity, and either overweight or obese, with oligomenorrhea being the most common presentation. The study concluded that WHR is a significant risk factor for metabolic syndrome in PCOS patients, highlighting the importance of focused management for obese women with PCOS.
