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Glossary Central Obesity

excessive fat accumulation around the abdomen and internal organs

Central obesity, also known as abdominal obesity, refers to the excessive accumulation of fat around the stomach and abdomen. This type of fat distribution is particularly concerning because it is associated with a higher risk of metabolic conditions such as type 2 diabetes, cardiovascular disease, and certain cancers. Unlike subcutaneous fat, which is stored just under the skin, central obesity involves visceral fat that surrounds internal organs, making it more harmful to overall health.

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research Central Obesity and BMI Associated with Different Phenotypes of Polycystic Ovary Syndrome in Adolescent

1 citations , December 2017 in “International Journal of Public Health Science (IJPHS)”

This study found no significant difference in obesity rates across various phenotypes of PCOS in high-school girls, but highlights the future health risks associated with hyperandrogenism.

Depression, Higher Level of Tension Induction, and Impaired Coping Strategies in Response to Stress in Women with PCOS Correlate with Clinical and Laboratory Indices of Hyperandrogenism and Not with Central Obesity and Insulin Resistance

research Depression, higher level of tension induction, and impaired coping strategies in response to stress in women with PCOS correlate with clinical and laboratory indices of hyperandrogenism and not with central obesity and insulin resistance

August 2024 in “Archives of Women s Mental Health”

This study found that women with PCOS exhibited higher levels of depression, tension induction, and impaired stress coping strategies compared to healthy controls, with these psychological issues correlating with hyperandrogenism but not with central obesity or insulin resistance.

research ACANTHOSIS NIGRICANS IN OBESE VERSUS NON-OBESE IN A TERTIARY CARE HOSPITAL ASSOCIATION WITH BMI AND CENTRAL OBESITY

June 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

This observational study found that benign and HAIR-AN were the most common acanthosis nigricans types associated with obesity, PCOS, and diabetes, highlighting the need for comprehensive screening in affected individuals.

research The Agouti Gene in Obesity: Central and Peripheral Mechanisms, and Therapeutic Implications

May 2001

This study found that dominant mutations in the mouse agouti gene lead to maturity-onset obesity, with weight increases starting around 4 weeks and peaking between 8 and 17 months.

research Insulin resistance and obesity among infertile women with different polycystic ovary syndrome phenotypes

42 citations , July 2017 in “Scientific Reports”

This study found that insulin resistance was significantly associated with PCOS among infertile women with central obesity, highlighting differences in insulin and phenotype severity.

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community I'm quitting finasteride after almost 3 years of daily use

in Finasteride/Dutasteride 166 upvotes 11 months ago

A 23-year-old stopped using finasteride due to sexual side effects after three years. The discussion covers experiences with finasteride, dutasteride, and other treatments, noting varied side effects and effectiveness.

community DHT Isn't (Directly) Important

101 upvotes 1 year ago

Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Dutasteride Infertility Debunked: Low T causes true infertility.

168 upvotes 1 year ago

Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.

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