1 citations
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December 2017 in “International Journal of Public Health Science (IJPHS)” This study found no significant difference in obesity rates across various phenotypes of PCOS in high-school girls, but highlights the future health risks associated with hyperandrogenism.
August 2024 in “Archives of Women s Mental Health” This study found that women with PCOS exhibited higher levels of depression, tension induction, and impaired stress coping strategies compared to healthy controls, with these psychological issues correlating with hyperandrogenism but not with central obesity or insulin resistance.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This observational study found that benign and HAIR-AN were the most common acanthosis nigricans types associated with obesity, PCOS, and diabetes, highlighting the need for comprehensive screening in affected individuals.
This study found that dominant mutations in the mouse agouti gene lead to maturity-onset obesity, with weight increases starting around 4 weeks and peaking between 8 and 17 months.
42 citations
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July 2017 in “Scientific Reports” This study found that insulin resistance was significantly associated with PCOS among infertile women with central obesity, highlighting differences in insulin and phenotype severity.
August 2026 in “Acta Dermato Venereologica” This study found that women with central centrifugal cicatricial alopecia had a substantial prevalence of systemic comorbidities, including strong associations with dyslipidemia, uterine leiomyomas, and anxiety disorders.
14 citations
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January 2018 in “Endocrinology and Metabolism” This study found that older age and obesity are predictors of metabolic syndrome and insulin resistance syndrome among infertile Vietnamese women with PCOS.
5 citations
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September 2022 in “International Journal of Health Sciences” This study found that hypothyroidism is more prevalent in older Indian females, with common symptoms including weight gain, weakness, and hair loss often associated with other conditions like type 2 diabetes and hypertension.
111 citations
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November 2010 in “Human Reproduction” This study found that young indigenous South Asian women with polycystic ovary syndrome are more likely to be centrally obese and have metabolic syndrome, particularly with increasing age, higher BMI, and acanthosis nigricans.
62 citations
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July 2017 in “Endocrine connections” This meta-analysis reported a significant association between polycystic ovary syndrome and an increased risk of obstructive sleep apnea in adult patients.
45 citations
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June 2012 in “JRSM Cardiovascular Disease” In this study, premature coronary artery disease in Indians under 40 was linked to factors like dyslipidemia, low HDL-C, smoking, and central obesity, with cutaneous markers significantly associated.
41 citations
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June 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.
30 citations
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November 2018 in “Fertility and Sterility” This study found that young women with polycystic ovary syndrome had a higher risk of developing hypertension and metabolic syndrome compared to healthy controls, although these risks decreased after age 40.
16 citations
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January 2016 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that men with early-onset androgenic alopecia had a higher prevalence of metabolic syndrome compared to controls without the condition.
12 citations
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January 2022 in “International Journal of Clinical Practice” This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.
7 citations
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October 2020 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that stress plays a significant role in altering phenotypic features and body composition among PCOS patients, potentially worsening due to the COVID-19 pandemic.
5 citations
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January 2018 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” In this study, flat feet were identified as a potential indicator of metabolic syndrome in obese individuals, with significant associations noted for striae distensae and candida intertrigo with abdominal obesity.
4 citations
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August 2018 in “Clinical Endocrinology” This study found that among women with polycystic ovary syndrome, insulin resistance was more strongly associated with cardio-metabolic abnormalities than β-cell dysfunction, and they showed different correlations with obesity.
4 citations
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April 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found a 21-fold increased risk of metabolic syndrome associated with a higher waist-hip ratio in women with polycystic ovary syndrome, highlighting the need for focused management in obese patients.
3 citations
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January 2013 in “Annals of Tropical Medicine and Public Health” In this study, adolescent females who were born via cesarean delivery, had at least one erupted wisdom tooth, or had central obesity were more likely to develop polycystic ovarian syndrome.
1 citations
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February 2021 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found a 6.11% prevalence of polycystic ovary syndrome among gynecology out-patients, noting that obese women with PCOS had more severe ovulatory dysfunction.
1 citations
,
April 2019 in “Endokrynologia Polska” This review discusses lifestyle interventions to manage weight and reduce metabolic consequences in women with PCOS but reports no new clinical results, highlighting the need for more randomized studies.
1 citations
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January 1990 in “Insula-revista De Letras Y Ciencias Humanas” This review reports that women with polycystic ovary syndrome have a 28%-50% higher risk of SARS-CoV-2 infection and more severe COVID-19 outcomes, linked to underlying metabolic and endocrine factors.
This study found that women with PCOS had significant hormonal imbalances, increased central obesity, and a lower 2D:4D digit ratio, suggesting prenatal androgen exposure may play a role in the condition's development.
March 2025 in “Forum Dermatologicum” This review explores links between metabolic syndrome and skin diseases, reporting shared mechanisms like inflammation and hormonal imbalances that may influence conditions such as acne, rosacea, psoriasis, and alopecia, and emphasizes the importance of managing cardiovascular risks in affected patients.
November 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This study discusses the multifactorial causes of metabolic syndrome and its association with various skin conditions, indicating an increased risk of diabetes and cardiovascular issues, emphasizing the need for early lifestyle interventions and medical management.
January 2023 in “Indian Dermatology Online Journal” This study found that female pattern hair loss in Western India is often associated with metabolic syndrome, which correlates with earlier onset and increased severity.
July 2018 in “Journal of Evolution of medical and Dental Sciences” In this study, researchers observed that men with androgenetic alopecia had a higher prevalence of metabolic syndrome compared to those without alopecia, which may warrant early screening for metabolic syndrome to prevent coronary artery disease, despite the study's small sample size.
May 2026 in “SJ Gynecology and Obstetrics Africa” In this study, younger women with PCOS showed a 27% prevalence of abnormal glucose tolerance, with higher rates among those who are obese, have central adiposity, acanthosis nigricans, or a family history of diabetes.
72 citations
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January 2007 in “Dermatology” This study found a correlation between moderate to extensive alopecia and low-grade inflammation, a cardiovascular risk marker, particularly in young men under 35 with central obesity.