Hidradenitis Suppurativa/Acne Inversa: An Endocrine Skin Disorder?

    Ioannis Karagiannidis, Georgios Nikolakis, Robert Sabat, Christos C. Zouboulis
    Studysummary This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 11

    1. Insulin Resistance and Skin Diseases The Scientific World Journal · 2015
    2. Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents JAMA Dermatology · 2013
    3. The Skin as an Endocrine Organ Dermato-endocrinology · 2009
    4. Hidradenitis Suppurativa Treated With Finasteride Journal of Dermatological Treatment · 2005
    5. The Human Skin as a Hormone Target and an Endocrine Gland Hormones · 2004
    6. Human Skin Is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003
    7. The SAHA Syndrome: Overview and Classification Hormone Research in Paediatrics · 2000
    8. Finasteride as a Therapy for Hidradenitis Suppurativa British Journal of Dermatology · 1999
    9. SAHA Syndrome: Female Androgenetic Alopecia and Hirsutism PubMed · 1999
    10. Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells: Evidence of Its Presence in Melanocytes Journal of Investigative Dermatology · 1998
    11. The Human Sebocyte Culture Model Provides New Insights Into Development and Management of Seborrhoea and Acne Dermatology · 1998

    Related research 3

    1. Spironolactone in Dermatology: Uses in Acne and Beyond Clinical and Experimental Dermatology · 2020
    2. Cutaneous Manifestations of Obesity and the Metabolic Syndrome Clinics in Dermatology · 2017
    3. Hidradenitis Suppurativa/Acne Inversa: An Endocrine Skin Disorder? Reviews in endocrine and metabolic disorders · 2016