The Skin as an Endocrine Organ

    September 2009 in “ Dermato-endocrinology
    Christos C. Zouboulis
    TLDR The skin produces and processes hormones, affecting both local and overall body functions.
    The document discussed the emerging understanding of the skin as an endocrine organ capable of producing, metabolizing, and responding to hormones through paracrine, autocrine, intracrine, and endocrine pathways. It highlighted that skin hormones play significant roles in overall human homeostasis and disorders, with implications for pharmacological and therapeutic applications, as evidenced by the use of corticosteroids, androgens, estrogens, vitamin D analogues, and retinoids in dermatology.
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