Cutaneous Manifestations of Obesity and the Metabolic Syndrome

The document from January 1, 2018, reviews the skin conditions associated with obesity and metabolic syndrome (MetS), indicating that obesity, with a BMI of ≥30 kg/m², is linked to a variety of skin disorders due to its impact on skin physiology. It lists conditions such as acanthosis nigricans, acrochordons, and psoriasis, noting that some are related to insulin resistance and others to the physical or inflammatory effects of obesity. The review also discusses the bidirectional relationship between psoriasis and obesity, the association of lichen planus with metabolic disturbances, and the increased risk of cardiovascular disease. It mentions that seborrheic dermatitis patients are more likely to have obesity-related conditions, and that gout and xanthoma are associated with diet and systemic disorders. The document underscores the importance of recognizing these cutaneous manifestations for early diagnosis and treatment to prevent serious long-term health issues.