This case report describes a middle-aged man with chronic tophaceous gout who experienced a rare form of non-scarring alopecia due to urate crystal deposition around hair follicles, leading to hair loss that remarkably improved with targeted treatment including allopurinol and lifestyle changes.
March 2025 in “European Journal of Medical Genetics”
This case report suggests that tofacitinib may effectively manage symptoms of AGS7 in a patient with an IFIH1 mutation, though further studies are needed to confirm its long-term safety and efficacy.
This study reported that Tianma Gouteng decoction improved hair follicle regeneration in mice and identified its potential mechanism, primarily involving the Wnt/β-catenin signaling pathway, through a combination of network pharmacology, molecular docking, and experimental validation.
April 2026 in “International Journal of Research and Review”
This article reviews current literature and suggests that managing gout with early urate-lowering therapy, within a 'treat-to-target' strategy, can help prevent systemic complications and address the rising prevalence of hyperuricemia-related diseases.