Investigating the Effects of Metabolic Dysregulation on Hair Follicles: A Comparison of HIV-Infected Women With and Without Central Lipohypertrophy

June 2013 in “ International Journal of Dermatology ”

Paradi Mirmirani, Toby Maurer, Mardge H. Cohen, G. D’Souza, Roksana Karim, Michael Plankey, Esther Robison, Anjali Sharma, Phyllis C. Tien, Nancy A. Hessol

metabolic dysregulation hair follicles central lipohypertrophy peripheral lipoatrophy scalp hair texture scalp inflammation eyelash length prostaglandin E2 eyelash follicles

TLDR Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

The study investigated the effects of metabolic dysregulation on hair follicles in 1,037 HIV-infected women, focusing on those with central lipohypertrophy. Among 76 women with central lipohypertrophy, there was a significant association with shorter eyelash length (OR 2.3; 95% CI 1.4-3.8) but no changes in scalp hair texture or inflammation. The findings suggested that prostaglandin E2 mediators might influence eyelash follicles, highlighting the need for further research on the link between central obesity and hair disorders in HIV-infected women.

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