Prostaglandin Analogs for Hair Growth: Great Expectations

    January 2003 in “ Dermatology online journal ”
    Ronni Wolf, Hagit Matz, Miriam Zalish, Ayala Pollack, Edith Orion
    TLDR Prostaglandin analogs like Latanoprost might help grow hair on the scalp and body.
    The document reviewed the potential of prostaglandin analogs, particularly latanoprost, for promoting hair growth. Initial observations showed that latanoprost stimulated eyelash growth and pigmentation in glaucoma patients. Clinical studies, including one with 43 patients, reported increased eyelash length and density. Experimental studies on macaques indicated that higher doses of latanoprost could induce moderate-to-marked scalp hair regrowth. The authors speculated that prostaglandin analogs might be more effective than current treatments like minoxidil and finasteride, suggesting they could become the first choice for treating androgenetic alopecia. However, they acknowledged that further research was needed to confirm these effects on different hair types.
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      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 3 months ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  55 upvotes 2 months ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 1 year ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  171 upvotes 1 day ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Compounded topicals

      in Female  6 upvotes 4 years ago
      BionicBell discussed using Bimatoprost, a medication typically for eyelash growth, for hair loss and mentioned a compounding pharmacy that can mix it with other ingredients like minoxidil and finasteride. They are seeking advice on using topical finasteride for female pattern baldness and are considering a custom foam combination to maximize hair growth results.

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