Cardiometabolic Risks in Polycystic Ovary Syndrome: Long-Term Population-Based Follow-Up Study

In a study involving 1702 women, with 178 diagnosed with polycystic ovary syndrome (PCOS) and 1524 serving as healthy controls, researchers found that women with PCOS under 40 years of age had a significantly higher risk of developing hypertension (HR 2.08) and metabolic syndrome (HR 1.81) compared to controls, with these risks diminishing after age 40. The risks for central obesity and obesity were also higher in the PCOS group under 40, but not significantly so after this age, and there was no significant difference in the risk of dyslipidemia between the two groups at any age. The study concluded that while young women with PCOS are at a higher risk for certain cardiometabolic conditions, these risks may decrease later in life, suggesting that cardiometabolic hazards associated with PCOS could diminish over time.