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Glossary Central Serous Chorioretinopathy

fluid buildup under retina causing visual distortion

Central Serous Chorioretinopathy (CSC) is an eye condition where fluid builds up under the retina, the light-sensitive layer at the back of the eye, causing visual distortion and blurred vision. This fluid accumulation is often due to a leak in the choroid, a layer of blood vessels behind the retina, and is commonly associated with stress and corticosteroid use.

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research Interventions for central serous chorioretinopathy: a network meta-analysis

87 citations , December 2015 in “Cochrane library”

This review observed limited evidence of clinically significant benefits from treatments for acute central serous chorioretinopathy, which often resolves spontaneously, but identified PDT and micropulse laser as the most promising for further trials.

research Minoxidil induced central serous Chorioretinopathy treated with oral Eplerenone – a case report

4 citations , June 2020 in “BMC Ophthalmology”

This case report suggests that prolonged use of topical minoxidil for androgenic alopecia may cause central serous chorioretinopathy, and oral eplerenone appeared effective in resolving symptoms in the patient presented.

research Minoxidil and bilateral central serous chorioretinopathy in an adolescent girl: relationship or causality?

1 citations , April 2025 in “Romanian Journal of Ophthalmology”

This study indicates that central serous chorioretinopathy linked to topical minoxidil use is rare, suggesting the need for early detection and discontinuation if it occurs.

research Short-Term Topical Minoxidil Use Associated with Acute Central Serous Chorioretinopathy: A Case Report

September 2025 in “Case Reports in Ophthalmology”

This case report suggests that even short-term use of topical minoxidil, as brief as one week, can induce central serous chorioretinopathy, which may resolve with medication discontinuation and observation.

Acute Central Serous Chorioretinopathy After Prolonged Application of Topical Minoxidil: A Case Report and Review of the Literature

research Acute central serous chorioretinopathy after prolonged application of topical minoxidil: A case report and review of the literature

April 2024 in “Indian journal of ophthalmology. Case reports”

This study reports a case of acute central serous chorioretinopathy potentially linked to prolonged topical minoxidil use for alopecia, with improvement following cessation of the treatment.

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