Acute Central Serous Chorioretinopathy After Prolonged Application of Topical Minoxidil: A Case Report and Review of the Literature

April 2024 in “ Indian journal of ophthalmology. Case reports ”

Jaydeep Walinjkar, Afroz Q Patel, Sundaram Natarajan

minoxidil androgenic alopecia central serous chorioretinopathy vascular permeability choroid subretinal space Rogaine hair loss CSCR

TLDR Using minoxidil for hair loss might rarely cause a vision problem where fluid builds up under the retina.

The document presents a case report of a 38-year-old man who developed acute central serous chorioretinopathy (CSCR) after using topical minoxidil for androgenic alopecia (hair loss) for 8 months. CSCR is a condition where fluid accumulates under the retina, causing it to detach, and it predominantly affects males. The patient's symptoms resolved 3 months after discontinuing minoxidil. The report suggests that minoxidil, which is used to promote hair growth, may increase vascular permeability in the choroid (the layer of blood vessels behind the retina), leading to fluid leakage into the subretinal space. However, the exact mechanisms are not fully understood. The authors conclude that while CSCR secondary to prolonged minoxidil use is infrequent, healthcare professionals should be aware of this potential risk.

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