Minoxidil Induced Central Serous Chorioretinopathy Treated with Oral Eplerenone – A Case Report

June 2020 in “ BMC Ophthalmology ”

Ramesh Venkatesh, Arpitha Pereira, Kuldeep Jain, Naresh Kumar Yadav

minoxidil androgenic alopecia eplerenone Central Serous Chorioretinopathy subretinal fluid Rogaine

Studysummary This case report suggests that prolonged use of topical minoxidil for androgenic alopecia may cause central serous chorioretinopathy, and oral eplerenone appeared effective in resolving symptoms in the patient presented. Our plain-language summary of this paper — not a Tressless recommendation.

In 2020, Venkatesh et al. conducted a case study on a 41-year-old male who developed Central Serous Chorioretinopathy (CSCR), a rare side-effect, after using a 5% topical minoxidil solution twice daily for 10 months to treat androgenic alopecia. Despite discontinuing the minoxidil treatment for 2 months, the patient's symptoms persisted. The patient was then treated with 50 mg/day of oral eplerenone for 4 weeks, which led to the complete resolution of his symptoms and subretinal fluid (SRF). There was no recurrence of SRF two months after starting the therapy. The study concluded that oral eplerenone was safe and effective in this case, but further studies are needed before it can be routinely used in the population.

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Research cited in this study

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