Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]

February 2020 in “ Drug Design Development and Therapy ”

Poonkiat Suchonwanit, Sasima Thammarucha, Kanchana Leerunyakul

minoxidil spironolactone female pattern hair loss hair shedding hair density urticaria postural hypotension facial hypertrichosis Sinclair hair shedding scale Rogaine

TLDR Low-dose Minoxidil combined with Spironolactone helps reduce hair loss and improve hair density in women, with some mild side effects.

In 2020, a review on the use of Minoxidil in hair disorders was corrected to state that a combination of low-dose Minoxidil (0.25 mg, not 2.5 mg as previously stated) and Spironolactone (25 mg) in patients with Female Pattern Hair Loss (FPHL) showed positive outcomes, including decreased hair shedding and improved hair density. The mean reduction in hair shedding score was 2.3 at 6 months and 2.6 at 12 months. Mild side effects such as urticaria, postural hypotension, and facial hypertrichosis were reported. The correction also clarified that the reduction in severity score relates to the visual-analogue Sinclair hair shedding scale.

View this study on dovepress.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Female. Telogen effluvium 4 years ago, hair still not back to normal

in Female 6 upvotes 7 years ago

A 23 year old female who experienced Telogen Effluvium due to stress 4 years ago, but her hair is still not back to normal. She is looking for treatments such as Minoxidil and dermarolling that may help with the thinning patches in her hair.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 1 month ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Spironolactone Update

in Female 11 upvotes 7 years ago

A woman's experience with Spironolactone as treatment for female pattern hair loss, including the effects of increasing dosage and her doctor's recommendation to try finasteride if no results are seen after 6 months. Other users have also shared their experiences with using finasteride for this condition.

community can someone please tell me its going to get better? im bawling my eyes out

in Female 67 upvotes 2 years ago

A 16-year-old girl is experiencing hair loss, which has worsened despite using minoxidil and multivitamins. Suggestions include broader hormone testing and considering other treatments like spironolactone if the hair loss is due to androgenic alopecia.

community Doctor says i shouldn't take fin because its "hormonal"

in Finasteride/Dutasteride 103 upvotes 4 months ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

Related Research

3 / 3 results

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations, January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Minoxidil can effectively treat patchy hair loss by stimulating hair growth.

research Alopecia Areata Treated With Topical Minoxidil

16 citations, April 1984 in “Archives of Dermatology”

Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.