TLDR Low-dose Minoxidil combined with Spironolactone helps reduce hair loss and improve hair density in women, with some mild side effects.
In 2020, a review on the use of Minoxidil in hair disorders was corrected to state that a combination of low-dose Minoxidil (0.25 mg, not 2.5 mg as previously stated) and Spironolactone (25 mg) in patients with Female Pattern Hair Loss (FPHL) showed positive outcomes, including decreased hair shedding and improved hair density. The mean reduction in hair shedding score was 2.3 at 6 months and 2.6 at 12 months. Mild side effects such as urticaria, postural hypotension, and facial hypertrichosis were reported. The correction also clarified that the reduction in severity score relates to the visual-analogue Sinclair hair shedding scale.
3 citations
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January 2018 A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
July 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” Minoxidil can effectively treat patchy hair loss by stimulating hair growth.
April 1985 in “Plastic & Reconstructive Surgery” A study conducted in 1985 with 30 patients evaluated the effects of 1% topical minoxidil on alopecia areata and alopecia totalis. The results showed a significant incidence of hair regrowth, with 16 patients achieving a cosmetically acceptable response. No side effects were reported. The study concluded that while topical minoxidil could induce new hair growth in cases of alopecia areata, it was less effective for more severe forms like alopecia universalis and totalis. Despite this, minoxidil was considered relatively non-toxic, easy to use, and free of systemic or local side effects compared to other treatments.
16 citations
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April 1984 in “Archives of Dermatology” Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.
