Interventions for Central Serous Chorioretinopathy: A Network Meta-Analysis

The network meta-analysis on interventions for central serous chorioretinopathy (CSC) included 25 studies with 1,098 participants and found that the overall quality of evidence was low due to small sample sizes and poor reporting. Treatments like anti-VEGF agents and photodynamic therapy (PDT) were compared, with PDT showing some promise in improving visual acuity and reducing recurrence. However, no single treatment demonstrated overwhelming efficacy, partly due to CSC's natural tendency to resolve spontaneously. The study highlighted the need for more high-quality, large-scale trials to determine the most effective interventions for CSC.