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GlossaryCancer Stem Cells (CSC)

small subset of tumor cells that can self-renew and differentiate

Cancer Stem Cells (CSCs) are a small subset of cells within a tumor that possess the ability to self-renew and differentiate into various cell types found in the cancer. These cells are thought to be responsible for tumor growth, metastasis, and recurrence after treatment, making them a critical target for cancer therapies.

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April 2016 in “JAMA Dermatology”

Acne is not a key diagnostic feature for PCOS, postadolescent men with acne may have insulin resistance, melanoma patients often have few moles, tumor size in CSCC indicates higher risk of serious outcomes, and hidradenitis suppurativa is linked to higher risk of heart problems and death.

research Stretching the Limits: From Homeostasis to Stem Cell Plasticity in Wound Healing and Cancer

124 citations, February 2018 in “Nature Reviews Genetics”

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

research Interventions for Central Serous Chorioretinopathy: A Network Meta-Analysis

87 citations, December 2015 in “Cochrane library”

No single treatment is clearly effective for central serous chorioretinopathy.

research Dormancy in the Stem Cell Niche

29 citations, March 2012 in “Stem Cell Research & Therapy”

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery

26 citations, December 2016 in “Pharmacology & Therapeutics”

New drugs for heart disease may be developed from molecules secreted by stem cells.

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community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community 10 Week Progress? 59M (Oral Dut, Supplements, and Topicals)

in Is this regrowth? 73 upvotes 3 weeks ago

The user is using a combination of oral Dutasteride, topical Minoxidil, Ketoconazole shampoo, and other supplements for hair regrowth, with plans to start microneedling. Some users see progress and suggest microneedling to enhance results, while others note that significant changes may take more time.