Metabolic and Reproductive Characteristics of First-Degree Relatives of Women with Self-Reported Oligo-Amenorrhea and Hirsutism

    October 2010 in “ Gynecological Endocrinology
    Assi Torvinen, Riitta Koivunen, Anneli Pouta, Stephen Franks, Hannu Martikainen, Aini Bloigu, Anna-Liisa Hartikainen, Mark I. McCarthy, Aimo Ruokonen, Marjo‐Riitta Järvelin, Laure Morin‐Papunen
    Image of study
    TLDR Relatives of women with PCOS symptoms are more likely to have similar health issues.
    The study focused on the prevalence of symptoms associated with Polycystic Ovary Syndrome (PCOS) among first-degree relatives of 98 women with oligo-amenorrhoea and hirsutism and 163 women without these symptoms. Data from 183 relatives of 43 symptomatic women and 412 relatives of 86 asymptomatic women revealed that mothers and sisters of symptomatic women were more likely to suffer from hirsutism, menstrual disorders, and infertility. Additionally, an increased prevalence of diabetes in sisters and hypertension in fathers of symptomatic women was observed. Despite limitations such as self-reported data and a small sample size, the study concluded that there is a higher risk of metabolic and reproductive disorders in the relatives of women with PCOS symptoms.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 12 results

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  56 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Why balding gets worse in every generation?

      in Chat  81 upvotes 5 months ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

    Related Research

    5 / 5 results