TLDR Relatives of women with PCOS symptoms are more likely to have similar health issues.
The study focused on the prevalence of symptoms associated with Polycystic Ovary Syndrome (PCOS) among first-degree relatives of 98 women with oligo-amenorrhoea and hirsutism and 163 women without these symptoms. Data from 183 relatives of 43 symptomatic women and 412 relatives of 86 asymptomatic women revealed that mothers and sisters of symptomatic women were more likely to suffer from hirsutism, menstrual disorders, and infertility. Additionally, an increased prevalence of diabetes in sisters and hypertension in fathers of symptomatic women was observed. Despite limitations such as self-reported data and a small sample size, the study concluded that there is a higher risk of metabolic and reproductive disorders in the relatives of women with PCOS symptoms.
61 citations,
February 2001 in “American Journal of Obstetrics and Gynecology” Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
1947 citations,
September 1995 in “New England journal of medicine/The New England journal of medicine” PCOS is a common hormonal disorder causing irregular periods and increased hair growth, linked to insulin resistance and long-term health issues.
14 citations,
February 2016 in “Journal of Obstetrics and Gynaecology Research” Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
1 citations,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
3 citations,
January 2012 in “Hanyang Medical Reviews” The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
85 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
1 citations,
April 1993 in “Problemy e̊ndokrinologii” Spironolactone effectively reduces symptoms of hyperandrogenism like hirsutism and acne.